Peptune Semax
A synthetic heptapeptide built on an ACTH fragment, studied in neurotrophic signalling research.
$45.00
In stock
- Class
- Heptapeptide
- Amount per vial
- 10 mg
- Form
- Lyophilized powder
- Length
- 7 residues
- CAS number
- 80714-61-0
- Molecular weight
- 813.9 g/mol
- Appearance
- White powder
For laboratory research use only · Certificate of analysis · Full specifications
Documentation
Certificate of analysis
No certificate is published for this product yet. Contact us to check the documentation for the current batch before you order; published certificates are listed in the documentation library.
Overview
About this product
Semax is a synthetic seven-residue peptide (Met-Glu-His-Phe-Pro-Gly-Pro). It is based on the ACTH(4-7) fragment, extended with Pro-Gly-Pro for stability, and it has no hormonal activity of its own in the models where it has been tested. The literature examines it in cell and rodent models of neurotrophic factor expression and neuronal signalling. It shares its stabilising Pro-Gly-Pro tail with Selank, which makes the pair a natural comparison in peptide-stability work. Supplied as a lyophilized powder in a sealed vial. What the research shows A 2006 rat study reported that a single administration of semax raised hippocampal BDNF protein by up to 1.4-fold and trkB tyrosine phosphorylation by 1.6-fold. A 2014 genome-wide study in rats with permanent middle cerebral artery occlusion found that semax mainly altered the expression of immune-related genes, and changed 24 vascular-system genes at 3 hours and 12 at 24 hours. A 2018 clinical study, published in Russian, followed 110 patients after ischaemic stroke divided into subgroups with and without semax and reported higher plasma BDNF levels with semax; its abstract does not describe randomisation or blinding. Sources: Dolotov et al., Brain Research, 2006, PMID 16996037. Medvedeva et al., BMC Genomics, 2014, PMID 24661604. Gusev et al., Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova, 2018, PMID 29798983. For laboratory research use only. Not for human or veterinary use. Purity and identity are stated on the batch certificate, published on this page once it is on file.
Research profile
Semax in the literature
Research areas · 0–5
The molecule
About this compound
Semax is a synthetic peptide of seven amino acids, sequence Met-Glu-His-Phe-Pro-Gly-Pro. It is an analogue of the ACTH fragment 4–10, with a Pro-Gly-Pro extension. The vial contains 10 mg.
- Class
- Heptapeptide
- Also known as
- ACTH (4–10) analogue, MEHFPGP
- CAS number
- 80714-61-0
- Sequence
- Met-Glu-His-Phe-Pro-Gly-Pro
- Length
- 7 residues
- Molecular formula
- C37H51N9O10S
- Molecular weight
- 813.9 g/mol
- Target in the literature
- Synthetic analogue of ACTH (4–10)
- Form
- Lyophilized powder
- Amount per vial
- 10 mg
- Appearance
- White powder
- Solubility
- Sterile water or bacteriostatic water
- Storage (unopened)
- −20 °C long term, 2 to 8 °C short term; sealed and away from light
- Storage (in solution)
- 2 to 8 °C, away from light; do not freeze
- Packaging
- Sealed vial
- Notes
- Related sequence: Analogue of ACTH (4–10)
Published research
These are published papers about the molecule. A paper is not a dose, not medical advice, and not evidence that this vial is for human or veterinary use.
- Semax, an ACTH(4-10) analogue with nootropic properties, activates dopaminergic and serotoninergic brain systems in rodents.
Neurochemical Research · 2005 · PMID 16362768
Rodent brain-chemistry measurements. The title is the paper's claim, not a claim about this vial.
- Functional Connectomic Approach to Studying Selank and Semax Effects.
Doklady Biological Sciences · 2020 · PMID 32342318
A brain-connectivity study in animals that included semax.
For laboratory research use only. Not for human or veterinary use. The amount on the label is the contents of the vial, not a dose.
Ordering in Canada
Buying Peptune Semax in Canada
- Can I buy Peptune Semax in Canada?
- Yes. Peptune sells Peptune Semax online for laboratory research use only, with tracked delivery to every province and territory in Canada.
- How much is Peptune Semax?
- 10 mg: $45, in Canadian dollars. Free shipping on orders of $150 or more.
- Is there a certificate of analysis for Peptune Semax?
- The certificate of analysis for the current batch of Peptune Semax is published on this page and in the COA library as soon as it is on file.
- How is Peptune Semax supplied?
- As a lyophilized powder in a sealed vial, labelled with the compound and the amount: 10 mg. The amount is the contents of the vial, not a dose. Keep it sealed, dry, cold and away from light.
- How do I pay?
- By Interac e-Transfer or crypto. The payment instructions arrive by email after you place the order, and nothing is charged before that step.
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